Recent results and performances from both Manchester United and Tottenham Hotspur mean that Saturday’s early kick-off is of real importance. United were level with Manchester City until their defensive and uninspiring goalless draw at Anfield was followed by defeat to newly-promoted Huddersfield Town last weekend, leaving them five points off top spot.

With 20 points they have been caught up by Spurs and are ahead courtesy of their goal difference from the early weeks of the season in which they were ruthless in front of goal. With Chelsea third and Arsenal fourth, the Red Devils cannot afford to drop further points in their quest to claim their first league title since Sir Alex Ferguson retired in 2013.

To give United and Jose Mourinho hope of a positive result, Tottenham confirmed on Friday that star striker Harry Kane – who has already scored 13 goals in all competitions -  suffered a hamstring in last weekend’s win over Liverpool at Wembley, meaning that he is unlikely to feature in this fixture. That will probably mean that Fernando Llorente deputises. The Spaniard, at 6ft 3in, will offer a different physical challenge for United’s defence and should not be underestimated. Along with City, United have the league’s best defensive record, with four conceded in nine games, so will see Kane’s absence, as well as their home form, as tipping the game in their favour.

Other than their midweek defeat in the EFL Cup with a much-changed line-up, Spurs have won six of their last seven games in all competitions, including a draw with Real Madrid at the Bernabeu, while their only defeat in the Premier League came to the champions Chelsea.

With all these aspects taken into account it is hard to predict what will happen on the Old Trafford pitch. However, Tipbet have a fantastic range of odds for this and every Premier League game. In the match winner markets, United, at 2.15, are rated as most likely to win – this is down to the fact that they have not lost a home match since September last year. It would not be a complete shock, however, for Spurs to end that run, and they are available at 3.65. In total 102 markets are available for this fixture, including the correct score.